David Warner

First on the list is Australia's veteran opening batsman David Warner. The left-hander has scored 1,226 runs against South Africa. He has smashed 139 fours and 25 sixes. Warner's highest score against the Proteas is 173 runs in the 5th ODI in Cape Town during Australia's tour of South Africa

Quinton de Kock

Second player in the list is South Africa's wicketkeeper-batsman Quinton de Kock. He has been a consistent run scorer for South Africa in the ICC World Cup 2023 and has so far registered four centuries to his name. He has scored 1,018 runs against the Aussies and has smashed 108 fours and 26 sixes. His highest score against Australia is 178 runs which came at SuperSport Centurion back in 2016

David Miller

David Miller is the third active player to score the most runs in Australia vs South Africa ODI clashes. Miller has recorded 932 runs against the Aussies and has 76 fours and 23 sixes registered under his name. His highest score is 139 runs which came in Hobart in the year 2011 during South Africa's tour of Australia

Steve Smith

Steve Smith has scored 703 runs in 22 ODI matches against the Proteas. The right-hander has recorded 63 fours and just 3 sixes against South Africa. His highest score is 108 runs which he scored during the 3rd ODI in Durban during the Australia tour of South Africa

Mitchell Marsh

Australia batsman Mitchell Marsh has scored 594 runs against South Africa and is the fifth active player on the list. Marsh has 52 fours and 22 sixes against Proteas and his highest score is 86 runs not out